BDBM50115579 (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid::2-Hydroxy-4-oxo-4-phenyl-but-2-enoic acid::2-Hydroxy-4-oxo-4-phenyl-but-2-enoic acid (0.25H2O)::CHEMBL16326::CHEMBL19332::CHEMBL467389::Sacchettini_CTRL

SMILES OC(=O)C(=O)CC(=O)c1ccccc1

InChI Key InChIKey=JGKFWCXVYCDKDU-UHFFFAOYSA-N

Data  5 KI  23 IC50  1 EC50

PDB links: 6 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50115579   

TargetPolymerase acidic protein(Hepatitis C virus)
University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50115579((Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid | 2-...)
Affinity DataKi:  480nMAssay Description:Binding affinity to PA N-terminal domain (Competitive)More data for this Ligand-Target Pair
TargetPolymerase acidic protein(Hepatitis C virus)
University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50115579((Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid | 2-...)
Affinity DataIC50:  2.13E+4nMAssay Description:Inhibitory concentration against cap-dependent endonuclease activity of influenza virus RNPMore data for this Ligand-Target Pair
TargetPolymerase acidic protein(Hepatitis C virus)
University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50115579((Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid | 2-...)
Affinity DataEC50:  2.07E+3nMAssay Description:Plaque growth inhibitionMore data for this Ligand-Target Pair
TargetPolymerase acidic protein(Hepatitis C virus)
University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50115579((Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid | 2-...)
Affinity DataIC50:  2.13E+4nMAssay Description:Inhibition of cap 1 ALMV primed Influenza transcriptaseMore data for this Ligand-Target Pair
TargetPolymerase acidic protein(Influenza A virus (strain A/X-31 H3N2))
Polo Universitario Ss. Annunziata

Curated by ChEMBL
LigandPNGBDBM50115579((Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid | 2-...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of recombinant Influenza A virus (A/X-31(H3N2)) N-terminal 6xHis-tagged PA-Nter (1 to 217 residues) expressed in Escherichia coli BL21-Cod...More data for this Ligand-Target Pair
TargetMalate synthase G [C619A](Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
D3R/Abbott

LigandPNGBDBM50115579((Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid | 2-...)
Affinity DataIC50:  2.00E+3nMAssay Description:DNTB-Coupled_Enzyme_AssayMore data for this Ligand-Target Pair